tweak

A sharp pinch or jerk; a twist or twitch.

A slight adjustment or modification.

(slang) Methamphetamine.

(slang) A single inhalation of cocaine.

An additional input to a block cipher, used in conjunction with the key to select the permutation computed by the cipher.

Trouble; distress; tweag.

(slang, no longer used) A prostitute.

To pinch and pull with a sudden jerk and twist; to twitch.

(informal) To adjust slightly; to fine-tune.

(US, slang) To exhibit extreme nervousness, evasiveness when confronted by authorities, compulsiveness, erratic motion, excitability, etc, due to or mimicking the symptoms of methamphetamine abuse.

(slang) To be extremely confused; to have no clue what is happening.

To tease, to annoy; to get under the skin of (someone, typically so as to irritate them, or by extension to enamor, frighten, etc).

(US, slang) To abuse methamphetamines, especially crystal meth.

From a catapult, to strike a target with a missile.