rankle /ˈɹæŋ.kəl/verb 2noun 1forms 4 verb2 •To cause irritation, bitterness or acrimony.My colleague's gratuitous criticism still rankles with me. •To fester.a splinter rankles in the flesh noun1 •(rare) A festering, embittering object or condition, either mental, or a physical sore or ulcer.To this the Prince appeared to acquiesce; but I saw it did not please, and left a rankle in his mind. — 1795 formsrankled · rankling · rankles · rankleth