protomolecule noun2 •A relatively simple molecule from which a more complex molecule is derived.It is most probable that all matter is simply the allotropic expression of one element and that the protomolecule is the union of the positively and negatively electrified etheric corpuscle. — 1912 •A collection of unstably bound atoms that has the potential to form a molecule if the structure can shed sufficient energy. formsprotomolecules