plague /pleɪɡ/noun 5verb 2forms 3phrases 1 noun5 •a deadly disease that reaches people from rats and spreads quickly from place to place •An epidemic or pandemic caused by any pestilence, but especially that caused by the above disease.Great plagues, such as the bubonic plague or smallpox or syphilis or influenza, can happen again. — 2006 •A widespread affliction, calamity, or destructive influx, especially when seen as divine retribution.Ten Biblical plagues over Egypt, ranging from locusts to the death of the crown prince, finally forced Pharaoh to let Moses's people go. •(figurative) A grave nuisance, whatever greatly irritates.Bart is an utter plague; his pranks never cease. •A group of common grackles (a blackbird), especially when flocking to e.g. parking lots at night.A plague of grackles hang out on wires on Friday, Dec. 16, 2022 in Houston. — 2024 verb2 •To harass, pester or annoy someone persistently or incessantly.Dame Gill did grin, As she went in, And Jill was plagu'd by Jack, Will Goat came by, And made Jack cry, And knock'd him on his back. — 1810 •To afflict with a disease or other calamity.Natural catastrophes plagued the colonists till they abandoned the pestilent marshland.Falling prices and drought plagued the cattle industry. formsplagued · plaguing · plagues Phrases with plague be at the plagueTo be bothered; to make the effort to do something.