pestilence /ˈpɛstələn(t)s/ noun2 •Any epidemic disease that is highly contagious, infectious, virulent and devastating.and hit was in the realme of Logrys and soo bifelle grete pestylence & grete harme to both Realmes "And it was in the realm of Logris; and so befell great pestilence and great harm to both realms." — 1485 •(no longer used) Anything harmful to morals or public order. formspestilences