CRISPR /ˈkrɪspər/noun 3verb 1forms 4 noun3 •Segments of bacteria and archaea DNA containing short repetitions of base sequences.Crispr is a guide molecule made of RNA, that allows a specific site of interest on the DNA double helix to be targeted. — 2018 •The CRISPR/Cas9 system, which functions to provide immunity to bacteria and archaea by finding a section of DNA and replacing it with an alternative.For the first time, doctors in the U.S. have used the powerful gene-editing technique CRISPR to try to treat a patient with a genetic disorder. — 2019 •Any technique or process or system for editing genomes by laboratory use of the CRISPR/Cas9 system. verb1 •(informal) To edit genomes by laboratory use of the CRISPR/Cas9 system.In this planned trial, doctors will remove cancer patients' T cells, “CRISPR” them, and then reinfuse them in the hope that they will recognize and attack the patients' cancers. — 2017 formsCRISPRed · CRISPRing · CRISPRs · Crisprs