cortical UK /ˈkɔː.tɪ.kəl/US /ˈkɔɹ.tɪ.kəl/ adjective2 •Pertaining to the outer layer of an internal organ or body structure, such as the kidney or the brain.An adult male skeleton from Wharram Percy showed fine-grained subperiosteal deposits of new bone on multiple skeletal elements, together with fine cortical pitting[…]. — 2023 •Pertaining to the cortex of a stem or root—the tissue that lies inward from the epidermis, but exterior to the vascular tissue.