bicyclic adjective 2noun 1forms 1 adjective2 •Having two cycles. •Having two rings of atoms in the molecule; the rings may be fused, as in naphthalene, or separate, as in biphenyl.[…] substitution of a carboxylate would be expected to destabilize the dritterionic mesomer that contributes to the singlet valence bond description as the benzyne geometry becomes more bicyclic. — 2003 noun1 •A bicyclic compound. formsbicyclics