tramadol /ˈtɹæm.əˌdɔl/ noun1 •A synthetic opioid analgesic administered orally in the form of its hydrochloride C₁₆H₂₅NO₂·HCl to treat moderate to severe pain.A nod from Rhona as she popped two tramadol and lay down on the couch again. — 2021 formstramadols