pain

noun7

1. •
   a feeling that hurts somewhere in the body, such as a headache

   • The greatest difficulty lies in treating patients with chronic pain.
   • I had to stop running when I started getting pains in my feet.
2. •
   [usually plural] The pangs or sufferings of childbirth, caused by contractions of the uterus.
3. •
   The condition or fact of suffering or anguish especially mental, as opposed to pleasure; torment; distress

   • In the final analysis, pain is a fact of life.
   • The pain of departure was difficult to bear.
4. •
   An annoying person or thing.

   • Your mother is a right pain.
5. •
   [in the plural] Labour; effort; great care or trouble taken in doing something.
6. •
   (old-fashioned) Suffering inflicted as punishment or penalty.

   • You may not leave this room on pain of death.
7. •
   (no longer used) Any of various breads stuffed with a filling.

verb5

1. •
   To hurt; to put to bodily uneasiness or anguish; to afflict with uneasy sensations of any degree of intensity; to torment; to torture.

   • The wound pained him.
2. •
   To render uneasy in mind; to disquiet; to distress; to grieve.

   • It pains me to say that I must let you go.
3. •
   (India) To feel pain; to hurt.

   • Please help me: I am paining hard.
4. •
   (old-fashioned) To hurt; to feel painful.

   • My infernal thumb pains yet like the very devil. — 1934
5. •
   (no longer used) To inflict suffering upon as a penalty; to punish.

noun1

1. •
   Acronym of pan-assay interference compound.