sclerotic UK /skləˈɹɒtɪk/US /skləˈɹɑtɪk/adjective 4noun 1forms 3 adjective4 •Having or relating to sclerosis; hardened.The outer wood exposed to the air may become carbonaceous due to the interaction of sclerotic mycelium and the wood. — 1920 •(figurative) Hard and insular; resistant to change.Most state parties--Democrat or Republican--are sclerotic and dutiful, and little help to local candidates. — 2018 •Of or relating to the sclera of the eye. •Of or relating to sclerotium. noun1 •Synonym of sclera.In front, this membrane is continuous with the cornea by direct continuity of tissue; but the opaque sclerotic overlaps it rather more on the outer than upon its inner surface. — 1859 formssclerotics · more sclerotic · most sclerotic