sclerosed

adjective3

1. •
   Hardened by sclerosis.
2. •
   lignified
3. •
   (figurative) Hardened; fixed; inflexible; tough.

   • "They are all good men." "Of course they are. It's quite physiological. They are a body of elderly men, and the elderly brain is sclerosed and cannot record new impressions." — 1925