progestogen UK /pɹəˈdʒɛs.tə.dʒən/US /pɹoʊˈdʒɛs.tə.dʒən/ noun2 •The steroid hormone progesterone. •Any of a class of synthetic hormones which produce effects similar to progesterone (the only natural progestogen) and have antiestrogenic and antigonadotropic properties. formsprogestogens