ossify UK /ˈɒs.ɪ.faɪ/US /ˈɑ.sə.faɪ/ verb4 •To transform (or cause to transform) from a softer animal substance into bone; particularly the processes of growth in humans and animals.[…], nor do all bones of the same skeleton ossify during the samе period of time. — 1884 •To become (or cause to become) inflexible and rigid in habits or opinions.Before long, the entire organization ossifies. — 1996 •To grow (or cause to grow) formulaic and permanent.This accidental repartition gets repeated, develops advantages of its own, and gradually ossifies into a systematic division of labour. — 1886 •To calcify.The cartilages become brittle, and in many instances are ossified; the ligaments are rendered harder, but are less capable of resisting extension. — 1850 formsossified · ossifying · ossifies