Miskito UK /ˈmɪs.kɪ.təʊ/US /ˈmɪs.kɪ.toʊ/adjective 1noun 1forms 1 adjective1 •Pertaining to a Native American people living in the region of Moskitia in Central America.Before I embarked, I found with the Doctor four Musquito Indians, who were chiefs in their own country, and were brought here by some English traders for some selfish ends. — 1789 noun1 •A member of these people; a Miskito Indian. formsMiskitos