selfish /ˈsɛl.fɪʃ/ adjective4 •putting personal comfort, money or pleasure first and giving little thought to others •Holding one's own self-interest as the standard for decision making. •Related to or equivalent to a selfish gene; best understood as existing to preserve and replicate itself in competition with other entities at the same level of existence, rather than at the level of the individual or population containing it.Through this hypothesized mechanism, a selfish virus would reduce the probability that other co-infecting genotypes contribute the expected share of their genes to the progeny. — 2005 •Of video game characters: relying on their own actions and capabilities to be effective in the game, rather than on other characters. formsmore selfish · selfisher · most selfish · selfishest