microtome noun 1verb 1forms 3 noun1 •A special instrument that produces very thin slices of plant and animal tissues, for later examination by light microscope or electron microscope.The first microtome was constructed for John Hill, to make the specimens described in his book on the structure of timber (1770). — 1998 verb1 •To cut into sections using a microtome formsmicrotomed · microtoming · microtomes