hypochondria UK /ˌhaɪpə(ʊ)ˈkɒndriə/US /ˌhaɪ.poʊˈkɒn.dri.ə/ noun2 •A formerly defined psychological disorder characterized by excessive preoccupation or worry about having a serious illness. No longer a current medical diagnosis; see hypochondriasis for more.In this category we must include, for example, hypochondria, a disturbance shown by undue anxiety concerning one's own physical and mental condition. — 1908 •(no longer used) Melancholy; depression.Such labours as these, if they do not shorten life, are calculated to make it wretched, for hypochondria invariably follows close upon them. — 1833 formshypochondrias