melancholy UK /ˈmɛlənkəli/US /ˈmɛl.ənˌkɑ.li/adjective 2noun 2forms 3 adjective2 •Suggestive of wistfulness or subdued emotion.It was the same old song / With a melancholy sound. — 1981 •(literary) Affected with great sadness or depression.Melancholy people don't talk much. noun2 •Great sadness or depression, especially of a thoughtful or introspective nature.My mind was troubled with deep melancholy. — 1591 •(historical) Black bile, formerly thought to be one of the four "cardinal humours" of animal bodies.Melancholy, cold and dry, thick, black, and sour, […] is a bridle to the other two hot humours, blood and choler, preserving them in the blood, and nourishing the bones. — 2001 formsmelancholies · more melancholy · most melancholy