epidural UK /ɛp.ɪˈdjʊə.ɹəl/US /ɛp.əˈd(j)ʊɹ.əl/adjective 2noun 1forms 3 adjective2 •Situated on or outside the dura mater. •Of or pertaining to the space immediately outside the dura mater.Epidural anesthesia is commonly used for pain relief during childbirth. noun1 •An injection of anaesthetic into the epidural space of the spine, especially associated with pain relief during childbirth. formsepidurals · more epidural · most epidural