deplete /dɪˈpliːt/verb 11forms 3 verb11 •To reduce the amount of; to remove (a substance from something)The winter storm quickly depleted the salt supply of the county. •To expend or separate a reactant. •To reduce the amount of a substance with a medication or medical procedure or due to a illness.Certain medications can deplete vitamin D. •To use up, exhaust, or consume (power or resources).Its reserves have been invaded and depleted. — 2007 •To decrease the amount of an isotope (in a mixture of isotopes). •To empty or purge (something of a substance).The conservation project depleted the lake of algae.This drug can deplete the body of magnesium. •To clear a compound or solution (of a reactant).Cycling also produces layered scales, as repeated spallation further depletes the compound of Al and allows Cr₂O₃ formation. — 2017 •To clear a mixture of isotopes (of an isotope or isotopes).The by-product of this process, which depletes uranium of its most radioactive isotopes, is called depleted uranium (DU). — 1999 •To diminish in quantity or strength; to be consumed.I noticed a couple of days ago how quickly the battery depletes.Depending on what you print, one color usually depletes faster than the others. •To be expended or separated (of a substance).As can be seen in Fig. 1.49, FS 21 rapidly depletes of Li⁺ near the surface during the exposure to a NaNO₃ melt and simultaneously enriches in Na⁺. — 2008 •To undergo loss of an isotope.Since uranium depletes in this process, it is called fissile fuel, nuclear fuel or simply fuel. — 2025 formsdepleted · depleting · depletes