Chicagoan /ʃɪˈkɑː.ɡoʊən/adjective 1noun 1forms 3 adjective1 •Of, from or relating to the city of Chicago, Illinois, United States. noun1 •A native or inhabitant of the city of Chicago, Illinois, United States.Chicago was the turning point of my journey and I left there at midnight abroad ^([sic]) the "Chicagoan," an express of the New York Central System. — 1953 formsChicagoans · more Chicagoan · most Chicagoan