carfentanil UK /kɑːˈfɛn.tə.nɪl/US /kɑɹˈfɛn.təˌnɪl/ noun1 •A narcotic painkiller that is four orders of magnitude more potent than morphine, used for tranquilizing large animals and abused as a recreational drug.He’d been hearing rumours lately of carfentanil in the supply line, which terrified him: one hundred times stronger than fentanyl, approved for the sole purpose of tranquilizing elephants. — 2020