cancerous /ˈkænsəɹəs/ adjective3 •Relating to or affected with cancer.On Sunday at five they operated to remove the cancerous kidney. — 2002 •(figurative) Growing or spreading rapidly to the point of harm. •(slang, offensive) Extremely unpleasant; detestable.I love this show, but the fanbase is so toxic and cancerous. formsmore cancerous · most cancerous