antipestilential adjective 1noun 1forms 3 adjective1 •Preventing or acting as a remedy against bubonic plague or other infectious diseases.Antipestilential Pills. — 1722 noun1 •A preventative or remedy against bubonic plague or other infectious diseases.Neither, as we may universally observe, is the Plague more shie in attaquing those that are armed with the said Antipestilentials, than others that slight all Preservatives. — 1665 formsantipestilentials · more antipestilential · most antipestilential