annotation /ˌæn.əˈteɪ.ʃən/ noun5 •A critical or explanatory commentary or analysis.She added an annotation in the margin to clarify the text. •A comment added to a text.The manuscript was filled with helpful annotations.The teacher asked students to submit essays with proper annotation. •Metadata added to a document or program. •The process of writing such comment or commentary. •Information relating to the genetic structure of sequences of bases. formsannotations