ALSer noun2 •(informal) A person with amyotrophic lateral sclerosis (ALS). •(Internet) A participant in the Usenet newsgroup alt.life.sucks.Good point. A blanket apology would be a good place to start if he really wants to be an ALSer. […] It will take a year or two to post the HUGE number of apologies he owes ALSers. — 1998 formsALSers