wirehouse noun2 •(US, Canada) A major brokerage company, generally nationwide, with multiple branches.Ten years ago, the Wall Street wirehouse brokerage firm seemed unassailable – part of the very firmament underpinning the entire investment industry from coast to coast. — 2012 •(US, no longer used) A brokerage company with a telegraph line, telephone line, or electronic communication network.The so-called ‘wire house’ …is a product of the boom times. — 1904 formswirehouses