wetware noun3 •(slang, humorous) The human brain or mind, likened to a computer part.… cyberpunk dream to leave behind the fallible "meat" or "wetware" of the body by entering the datasphere ... — 2001 •(slang, humorous) Organic or biological matter in general. •The underlying generative code for an organism, as found in the genetic material, in the biochemistry of the cells, or in the architecture of the body’s tissues.