Wessex /ˈwɛs.ɪks/ noun2 •The West Country, a geographic area in the south west of England.And I said I’d couch-surfed around Wessex and Wales and had a good time, and the train ride from Devon to Scotland was long and smoky […] — 2001 •(historical) One of the seven major Anglo-Saxon kingdoms, existing between the 6th and 9th centuries, and comprising most of England south of the Thames.