Weltschmerz

noun1

1. •
   An apathetic or pessimistic view of life; depression concerning or discomfort with the human condition or state of the world; mal du siècle, world-weariness.

   • Here we have it at once, blended though it may be with the new elements of purging humour and all-embracing Weltschmerz, in [William] Shakespeare's Hamlet. — 1938