wazoo /wɑˈzu/ noun2 •(slang) The anus."When you get burned once," Markham continued, "as I did in 'Second Hundred Years' ... where I got my wazoo shot off ..." — 1969 •(slang) A horrible person; an arsehole.Even now, in the spring, the river softly cries, 'Menthol, Menthol, you are one wazoo. One day I'm the elf next door and the poof I'm a river.' — 1969 formswazoos