unsane adjective3 •Not sane. •Synonym of insane.If only he didn’t feel so tired, so sick of everything, his father, this unsane country. — 2023 •In a state of maladaptive mental functioning that is not insane (that is, not mentally ill, or at least not clinically so) but is also not sane under a definition whereby sanity is highly adaptive cognition. formsmore unsane · most unsane