two-handed adjective 5adverb 1 adjective5 •Using or designed for use by both hands at once. •Involving, or designed for use by, two people.a two-handed game of cards •Ambidextrous. •Having two hands. •(slang, old-fashioned) Good with one's fists; able to fight well.The Baker was a two-handed hitter, and seemed perfectly awake to the business before him. — 1845 adverb1 •In a two-handed manner.