twerp UK /twɜːp/US /twɝp/ noun3 •(informal) A fool, a twit.Now you've broken it, you twerp! •(informal) A small or puny person; one regarded as insignificant, contemptible.Get out of my way, you little twerp! •(US, informal) A person who can be bullied playfully, or easily teased. Sometimes used as a pet-name (often for a younger sibling). formstwerps