tweaky adjective2 •(informal) Showing signs of methamphetamine intoxication or involvement, or otherwise related to methamphetamine or similar drugs.I don't need no tweaky twink / Making meth under his sink / Don't you think it's time for bed? — 2012 •(informal) Involving minor adjustments.As with most hacker tools, however, iPodWizard is a bit of a tweaky program, which means it's not for the faint of heart or for those utterly devoid of technical skills. — 2007 formstweakier · tweakiest