systole /ˈsɪstəli/ noun4 •The rhythmic contraction of the heart, by which blood is driven through the arteries.A double systole catapulted him into full consciousness again, and he promised his uncorrected self that he would limit his daily ration of cigarettes to a couple of heartbeats. — 1972 •The contraction of the contractile vesicles in certain algae, plasmodia, and zoospores. •(rhetoric) A shortening of a naturally long vowel. •The shortest noncontractible loop on a compact metric space. formssystoles