syndesmosis UK /ˌsɪn.dɛzˈməʊ.sɪs/US /ˌsɪn.dɛzˈmoʊ.sɪs/ noun1 •A slightly movable articulation or joint where the contiguous bony surfaces are rough and are united by an interosseous ligament (e.g. between the fibula and tibia at the ankle).He was diagnosed with syndesmosis in his left ankle, the same injury that cost Ryan Hoffman a place in last year's grand final. — 2009 formssyndesmoses