stupefy

verb3

1. •
   To dull the senses or capacity to think thereby reducing responsiveness; to stun.

   • a stupefying drug; a stupefacient
   • He stupefied her by means of chloroform, a general anaesthetic.
2. •
   (figurative) To astonish or stun, especially as a result of some distressing action.

   • The police's negligence and callousness continued to stupefy her.
3. •
   (no longer used) To deprive a material of the ability to undergo change or movement, especially deformation.

   • The next is, when it is not malleable, but yet it is not fluent, but stupified^([sic]). — 1631