start up UK /stɑːˈtʌp/US /stɑɹˈtʌp/ verb5 •To commence the operation of; to activate; to launch.The four of them started up a law practice. •To begin to operate.The engine started up right away. •To begin.The band started up playing. •To begin to make a soundFirst a solitary blackbird started up, but soon the whole forest was alive with birdsong. •To rise suddenly.He started up when he heard the scream. formsstarted up · starting up · starts up