spithole noun2 •(slang) A person's mouth.Plug up yer spithole. Yer nothin but a pile of shitty peacock feathers. Sew up the hole in yer tights and get outta here. Go over to araa where someone will listen to ya. — 1999 •(euphemistic) Euphemistic form of shithole.HEB is a spithole and I wouldn't go in there if they were giving everything away. — 1999 formsspitholes