sleeping sickness /ˈsliːpɪŋ ˈsɪknɪs/ noun5 •Any of several diseases of which lethargy is a major symptom. •Especially, African sleeping sickness, an endemic infectious disease of humans and animals in tropical Africa, caused by a parasitic trypanosome. •Animal trypanosomiasis. •Eastern equine encephalitis, caused by a zoonotic alphavirus and arbovirus present in North, Central and South America and the Caribbean. •Encephalitis lethargica, a form of encephalitis, of unknown cause, that swept the world in the 1920s. formssleeping sicknesses