senescence

noun5

1. •
   The state or process of ageing, especially in humans; old age.
2. •
   Old age; accumulated damage to macromolecules, cells, tissues and organs with the passage of time.
3. •
   Fruit senescence, leading to ripening of fruit.
4. •
   Ceasing to divide by mitosis because of shortening of telomeres or excessive DNA damage.

   • Tests in mice found that inducing senescence in bile duct cells - mimicking the process seen in human bile duct disease - led to liver scarring and damage of liver function. — 2018
5. •
   Condition when the cell ceases to divide.