sclerogenous adjective2 •Making or secreting a hard substance; becoming hard.In the outermost rows of this zone are a large number of sclerogenous cells, forming isolated groups; these occur here and there, but less numerously, in the remainder of the zone. — 1877 •Characterized by or causing a hardening of tissue.This observation is based on the minute histopathological study of 48 cases of Botkin's disseas and 102 cases of sclerogenous hepatitis . — 1958 formsmore sclerogenous · most sclerogenous