santorum /sanˈtɔːɹəm/ noun2 •(slang, vulgar) A frothy mixture of lubricant and fecal matter as an occasional byproduct of anal sex.She wads up the t-shirt, uses it to wipe a trickle of santorum from her ass, and throws it under the cot. — 2005 •(slang, disapproving) Shit: rubbish, worthless matter, nonsense, bull.a lying sack of santorum. — 2004