quadrivalent /kwɒdrɪˈveɪlənt/adjective 3noun 1forms 1 adjective3 •Having a valence of four. •Protecting against four different (usually influenza) viruses. •Having all of its vertices of degree four.In graph theory terms, a regular projection of a knot, or knot diagram is thus a quadrivalent planar graph with over/under-decorated vertices. — 2020 noun1 •Any quadrivalent chromosome formsquadrivalents