profitably UK /ˈpɹɒf.ɪ.tə.bli/US /ˈpɹɑ.fɪ.tə.bli/ adverb1 •In a profitable manner, in a way that achieves profit or gain.[…] that person is hardly susceptible to blackmail. One cannot profitably threaten to broadcast to others what is already known. — 1971 formsmore profitably · most profitably