pramipexole UK /ˌpɹæm.ɪˈpɛk.səʊl/US /ˌpɹæm.ɪˈpɛkˌsoʊl/ noun1 •A dopamine agonist administered in the form of its dihydrochloride C₁₀H₁₇N₃S·2HCl to treat the symptoms of Parkinson's disease.