poofy /ˈpuːfi/ adjective3 •(slang) Of or pertaining to something that is puffy, filled with air, inflated.Hey, look at that dust cloud. It's so... poofy! Poof! — 2006 •(slang, offensive) Pertaining to or describing homosexual behaviour or culture.Contraception was a taboo subject. The boys thought 'dunkies' (condoms) were poofy and anyway 'it's up to the girl to think about that because she's the one who gets the baby'. — 2019 •Capable of making a poofing sound. formspoofier · poofiest