Poindexter UK /ˈpɔɪnˌdɛkstə/US /ˈpɔɪnˌdɛkstɚ/ noun1 •(US, informal) A bookish or socially unskilled person.Brain: A quantum-interface bomb? Are you insane in the membrane? / Philip Fry: You got it, Poindexter! — 2003 formsPoindexters · poindexters